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Anti-EMP-1 Polyclonal Antibody
(Synonyms: Tumor-associated membrane protein, TMP, Protein B4B, Epithelial membrane protein 1, EMP1, EMP 1, CL-20) Copy Product Info
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Synonyms: Tumor-associated membrane protein, TMP, Protein B4B, Epithelial membrane protein 1, EMP1, EMP 1, CL-20
Catalog No. TMAB-00607 Copy Product Info
🥰Excellent
Anti-EMP-1 Polyclonal Antibody is a Rabbit antibody targeting EMP-1. Anti-EMP-1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-EMP-1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-EMP-1 Polyclonal Antibody is a Rabbit antibody targeting EMP-1. Anti-EMP-1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Tumor-associated membrane protein, TMP, Protein B4B, Epithelial membrane protein 1, EMP1, EMP 1, CL-20 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer. |
| Immunogen | KLH conjugated synthetic peptide: mouse EMP-1 |
| Antigen Species | Mouse |
| Gene Name | Emp1 |
| Protein Name | Epithelial membrane protein 1 |
| Molecular Weight | Theoretical: 17 kDa. Actual: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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