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3-Epideoxycholic Acid

🥰Excellent
Catalog No. T84944Cas No. 570-63-8
Alias EDCA

3-Epideoxycholic Acid is a secondary bile acid, a microbial metabolite of Deoxycholic acid. It targets the FXR receptor on dendritic cells, reducing their immunostimulatory properties, increasing Foxp3 induction, and promoting the generation of regulatory T cells (Tregs), thereby exhibiting anti-inflammatory activity.

3-Epideoxycholic Acid

3-Epideoxycholic Acid

🥰Excellent
Purity: 99.433%
Catalog No. T84944Alias EDCACas No. 570-63-8
3-Epideoxycholic Acid is a secondary bile acid, a microbial metabolite of Deoxycholic acid. It targets the FXR receptor on dendritic cells, reducing their immunostimulatory properties, increasing Foxp3 induction, and promoting the generation of regulatory T cells (Tregs), thereby exhibiting anti-inflammatory activity.
Pack SizePriceAvailabilityQuantity
1 mg$60In Stock
5 mg$228In Stock
10 mg$396In Stock
25 mg$663In Stock
50 mg$927In Stock
100 mg$1,230In Stock
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Purity:99.433%
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Product Introduction

Bioactivity
Description
3-Epideoxycholic Acid is a secondary bile acid, a microbial metabolite of Deoxycholic acid. It targets the FXR receptor on dendritic cells, reducing their immunostimulatory properties, increasing Foxp3 induction, and promoting the generation of regulatory T cells (Tregs), thereby exhibiting anti-inflammatory activity.
SynonymsEDCA
Chemical Properties
Molecular Weight392.57
FormulaC24H40O4
Cas No.570-63-8
SmilesC[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 200 mg/mL (509.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5473 mL12.7366 mL25.4732 mL127.3658 mL
5 mM0.5095 mL2.5473 mL5.0946 mL25.4732 mL
10 mM0.2547 mL1.2737 mL2.5473 mL12.7366 mL
20 mM0.1274 mL0.6368 mL1.2737 mL6.3683 mL
50 mM0.0509 mL0.2547 mL0.5095 mL2.5473 mL
100 mM0.0255 mL0.1274 mL0.2547 mL1.2737 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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