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Anti-Integrin alpha 2 Antibody (2R979) is a Rabbit antibody targeting Integrin alpha 2. Anti-Integrin alpha 2 Antibody (2R979) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-Integrin alpha 2 Antibody (2R979) is a Rabbit antibody targeting Integrin alpha 2. Anti-Integrin alpha 2 Antibody (2R979) can be used in WB,ICC/IF,IHC,IP,FCM. |
Alias | VLA2 alpha chain, VLA 2 subunit alpha, VLA 2 alpha chain, VLA 2, Very late activation protein 2 receptor alpha 2 subunit, Platelet receptor for collagen, deficiency of, included, Platelet membrane glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet glycoprotein Ia, Platelet glycoprotein GPIa, Platelet antigen Br, Platelet alloantigen Br(a), included, Itga2, ITA2, HPA5 included, HPA 5 included, GPIa, GP Ia deficiency, included, GP Ia, Glycoprotein Ia deficiency included, DX5, Collagen receptor, CD49b antigen, CD49b, CD49 antigen like family member B, CD 49b |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The sixteen α and eight β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counter-receptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Integrin α2 is responsible for adhesion of platelets and other cells to collagens. Modulation of collagen and collagenase gene expression force generation and organization of newly synthesized extracellular matrix. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 150 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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