IL-22BP Protein, Human, Recombinant (His)

Name: IL-22BP Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07035
Rating: 4.5 (1 reviews)

(Synonyms: ZCYTOR16, UNQ5793/PRO19598/PRO19822, IL-22R-alpha-2, IL-22RA2, IL-22BP, CRF2X, CRF2-S1, CRF2-10) Copy Product Info

Synonyms: ZCYTOR16, UNQ5793/PRO19598/PRO19822, IL-22R-alpha-2, IL-22RA2, IL-22BP, CRF2X, CRF2-S1, CRF2-10

Catalog No. TMPY-07035 Copy Product Info

IL-22BP Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q969J5-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$93	7-10 days	7-10 days
10 µg	$152	7-10 days	7-10 days
20 µg	$248	7-10 days	7-10 days
50 µg	$497	7-10 days	7-10 days
100 µg	$833	7-10 days	7-10 days
200 µg	$1,380	7-10 days	7-10 days
500 µg	$2,730	7-10 days	7-10 days
1 mg	$5,280	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	IL-22BP Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q969J5-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q969J5-1
Construction	A DNA sequence encoding the human IL22RA2 (NP_443194.1) (Met1-Pro263) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	> 95% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	ZCYTOR16, UNQ5793/PRO19598/PRO19822, IL-22R-alpha-2, IL-22RA2, IL-22BP, CRF2X, CRF2-S1, CRF2-10
Research Background	Interleukin-22 receptor subunit alpha-2 (IL-22RA2), also known as interleukin-22-binding protein (IL-22BP), is a subunit of the receptor for interleukin 22. IL-22BP belongs to the type II cytokine receptor family and contains 3 fibronectin type-III domains. IL-22BP/IL-22RA2 is expressed in a range of tissues, including those in the digestive, female reproductive, and immune systems. It is expressed in the placenta, spleen, breast, skin, and lung. It is also detected in the intestinal tract, testis, brain, heart, and thymus. The dominant cell types expressing IL-22BP/IL-22RA2 were mononuclear cells and epithelium. IL-22BP/IL-22RA2 may play an important role as an IL-22 antagonist in the regulation of inflammatory responses. Interleukin-22 (IL-22) is a member of the IL-10 family. It is produced by T cells and induces the production of acute-phase reactants. IL-22 plays important role in the immune response through activation of the STAT 3 signal transduction pathway. Two types of IL-22-binding receptors have been discovered, a membrane-bound receptor and a soluble receptor.

Chemical Properties

Molecular Weight

29.7 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.