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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | TBDMS-PEG4-OH is a PEG-based linker for PROTACs (Proteolysis Targeting Chimeras) that joins two essential ligands, facilitating the selective degradation of proteins by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two distinct ligands joined by a linker: one ligand targets an E3 ubiquitin ligase, while the other binds to the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1]. |
Molecular Weight | 308.49 |
Formula | C14H32O5Si |
Cas No. | 134179-40-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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