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Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not contain a predicted signal sequence or transmembrane domains. CPNE1 may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 has a broad tissue distribution and it may function in membrane trafficking.

| Pack Size | Price | Availability | Quantity | 
|---|---|---|---|
| 5 μg | $72 | 7-10 days | |
| 10 μg | $116 | 7-10 days | |
| 20 μg | $186 | 7-10 days | |
| 50 μg | $352 | 7-10 days | |
| 100 μg | $582 | 7-10 days | |
| 200 μg | $967 | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. | 
| Description | Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not contain a predicted signal sequence or transmembrane domains. CPNE1 may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 has a broad tissue distribution and it may function in membrane trafficking. | 
| Species | Human | 
| Expression System | E. coli | 
| Tag | N, C-6xHis | 
| Accession Number | Q99829 | 
| Synonyms | CPNE1,CPN1,Copine-1,Copine I | 
| Amino Acid | Met1-Ala537 | 
| Construction | Met1-Ala537 | 
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) | 
| Molecular Weight | 58-66 KDa (reducing condition) | 
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. | 
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. | 
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. | 
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| Research Background | Copine-1(CPNE1) encodes a calcium-dependent protein which belongs to the copine family. CPNE1contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, CPNE1 does not contain a predicted signal sequence or transmembrane domains. CPNE1 may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 has a broad tissue distribution and it may function in membrane trafficking. | 

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