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Anti-Transferrin Receptor/TFRC Antibody-APC (6G357)
🥰Excellent
Catalog No. TMAY-01475A
Anti-Transferrin Receptor/TFRC Antibody-APC (6G357) is a APC-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-APC (6G357) can be used in FCM.
Anti-Transferrin Receptor/TFRC Antibody-APC (6G357)
Anti-Transferrin Receptor/TFRC Antibody-APC (6G357)
🥰Excellent
Catalog No. TMAY-01475A
Anti-Transferrin Receptor/TFRC Antibody-APC (6G357) is a APC-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-APC (6G357) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Transferrin Receptor/TFRC Antibody-APC (6G357) is a APC-conjugated Mouse antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody-APC (6G357) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6G357 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human TFRC(CD71) expression on U937 cells. Cells were stained with APC-conjugated anti-Human TFRC(CD71). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin Receptor / TFRC / CD71 (rh Transferrin Receptor / TFRC / CD71; TMPY-01873; AAA61153.1; Cys89-Phe760) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Conjucates | APC |
| Others Formats | Unconjugated/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human Transferrin Receptor / TFRC / CD71 Protein (TMPY-01873) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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