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NAADP sodium

Name: NAADP sodium
Brand: TargetMol
SKU: T35922
Rating: 4.5 (1 reviews)

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Catalog No. T35922

NAADP sodium is a Ca2+ mobilizing second messenger that targets a novel Ca(2+) channel located on acidic organelles and indirectly activates TPC by binding to NAADP-binding proteins (NAADP-BPs) that form part of the TPC complex, which can be used to study cancer and immune dysfunction.F13714 fumarate is used in the study of leukemia.GSK321 is used in the study of leukemia.GSK321 is used in the study of leukemia.

NAADP sodium

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Catalog No. T35922

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$223	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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COA

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	744.39
Formula	C₂₁H₂₇N₆O₁₈P₃
Smiles	C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)(O)[O-])O)O)O)C(=O)O

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20 mg/mL (26.87 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.3434 mL	6.7169 mL	13.4338 mL	67.1691 mL
5 mM	0.2687 mL	1.3434 mL	2.6868 mL	13.4338 mL
10 mM	0.1343 mL	0.6717 mL	1.3434 mL	6.7169 mL
20 mM	0.0672 mL	0.3358 mL	0.6717 mL	3.3585 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc