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Penconazole

Name: Penconazole
Brand: TargetMol
SKU: T9802
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9802Cas No. 66246-88-6

Penconazole is a broad-spectrum and highly effective triazole antifungal agent that acts by inhibiting fungal sterol biosynthesis. Penconazole induces oxidative stress in rat brain and cerebellum tissues and inhibits AChE activity.

Penconazole

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Purity: 98.68%

Catalog No. T9802Cas No. 66246-88-6

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$31	-	In Stock
500 mg	$88	-	In Stock
1 mL x 10 mM (in DMSO)	$39	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.68%

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COA LCMS

Product Introduction

Bioactivity

Description	Penconazole is a broad-spectrum and highly effective triazole antifungal agent that acts by inhibiting fungal sterol biosynthesis. Penconazole induces oxidative stress in rat brain and cerebellum tissues and inhibits AChE activity.
In vivo	Methods: Penconazole (67 mg/kg, intraperitoneal injection, 19 days) was administered to male Wistar rats to investigate its potential toxic effects on the cerebrum and cerebellum of adult rats. Results: Penconazole induced oxidative stress in rat cerebrum and cerebellum tissues. [2]

Chemical Properties

Molecular Weight	284.18
Formula	C₁₃H₁₅Cl₂N₃
Cas No.	66246-88-6
Smiles	ClC1=CC=C(C(Cl)=C1)C(CN2N=CN=C2)CCC
Relative Density.	1.2556 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (281.51 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (11.61 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5189 mL	17.5945 mL	35.1890 mL	175.9448 mL
5 mM	0.7038 mL	3.5189 mL	7.0378 mL	35.1890 mL
10 mM	0.3519 mL	1.7594 mL	3.5189 mL	17.5945 mL
20 mM	0.1759 mL	0.8797 mL	1.7594 mL	8.7972 mL
50 mM	0.0704 mL	0.3519 mL	0.7038 mL	3.5189 mL
100 mM	0.0352 mL	0.1759 mL	0.3519 mL	1.7594 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc