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6-Hydroxynicotinic acid

🥰Excellent
Catalog No. T4816Cas No. 5006-66-6
Alias 6-Hydroxypyridine-3-carboxylic acid, 2-Hydroxy-5-pyridinecarboxylic acid

6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6-hydroxynicotinic acid from nicotinic acid.

6-Hydroxynicotinic acid

6-Hydroxynicotinic acid

🥰Excellent
Purity: 98.98%
Catalog No. T4816Alias 6-Hydroxypyridine-3-carboxylic acid, 2-Hydroxy-5-pyridinecarboxylic acidCas No. 5006-66-6
6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6-hydroxynicotinic acid from nicotinic acid.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 g$29-In Stock
1 mL x 10 mM (in DMSO)$29In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.98%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is exploited in the use of NMR spectroscopy or gas chromatography--mass spectrometry for the diagnosis of Pseudomonas aeruginosa in urinary tract infection. Among the common bacteria causing urinary infection, only P. aeruginosa produces 6-hydroxynicotinic acid from nicotinic acid.
Synonyms6-Hydroxypyridine-3-carboxylic acid, 2-Hydroxy-5-pyridinecarboxylic acid
Chemical Properties
Molecular Weight139.11
FormulaC6H5NO3
Cas No.5006-66-6
SmilesOC(=O)C1=CC=C(O)N=C1
Relative Density.1.451 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (359.43 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (7.19 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM7.1886 mL35.9428 mL71.8856 mL359.4278 mL
5 mM1.4377 mL7.1886 mL14.3771 mL71.8856 mL
10 mM0.7189 mL3.5943 mL7.1886 mL35.9428 mL
20 mM0.3594 mL1.7971 mL3.5943 mL17.9714 mL
50 mM0.1438 mL0.7189 mL1.4377 mL7.1886 mL
100 mM0.0719 mL0.3594 mL0.7189 mL3.5943 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

InhibitorinhibitEndogenousMetaboliteEndogenous Metabolite6-Hydroxynicotinic acid6Hydroxynicotinic acid6 Hydroxynicotinic acid
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