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Oxytocin antiparallel dimer TFA is a homo peptide dimer connected by a disulfide bridge, exhibiting activities similar to oxytocin and vasopressin but with reduced toxicity [1] [2].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Oxytocin antiparallel dimer TFA is a homo peptide dimer connected by a disulfide bridge, exhibiting activities similar to oxytocin and vasopressin but with reduced toxicity [1] [2]. |
| In vitro | The biological activity of parallel and antiparallel, homodimeric/heterodimeric disulfide-linked dimers of oxytocin and deamino-oxytocin ranges from 0.2% to 6% of that of oxytocin [1]. |
| In vivo | Oxytocin dimer, when administered intravenously (静脉注射) as a single dose (单剂量), exhibits lower acute toxicity in rats compared to oxytocin, with an LD50 of 43 mg/kg versus 25 mg/kg [2]. |
| Sequence | H-Cys(1)-Tyr-Ile-Gln-Asn-Cys(2)-Pro-Leu-Gly-NH2.H-Cys(2)-DL-Tyr-Ile-DL-Gln-Asn-DL-Cys(1)-Pro-Leu-Gly-NH2 |
| Sequence Short | Sequence 1:CYIQNCPLG;Sequence 2:CYIQNCPLG (Disulfide bridge:Chain1 Cys1 to Chain2 Cys6;Chain1 Cys6 to Chain2 Cys1) |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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