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Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: Transforming growth factor β-2, Transforming growth factor beta-2 proprotein, TGF-β-2, TGFβ2, TGF-beta-2, TGFB2, Latent TGF-β2) Copy Product Info

Synonyms: Transforming growth factor β-2, Transforming growth factor beta-2 proprotein, TGF-β-2, TGFβ2, TGF-beta-2, TGFB2, Latent TGF-β2

Catalog No. TMPJ-00260 Copy Product Info
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$3187-10 days7-10 days
10 µg$5337-10 days7-10 days
20 µg$9007-10 days7-10 days
50 µg$1,5807-10 days7-10 days
100 µg$2,4807-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812.
Species
Human
Expression System
HEK293 Cells
TagN-8xHis-Avi
Accession NumberP61812
Amino AcidLeu30-Ser390
ConstructionLeu30-Ser390 (Cys33Ser)
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTransforming growth factor β-2, Transforming growth factor beta-2 proprotein, TGF-β-2, TGFβ2, TGF-beta-2, TGFB2, Latent TGF-β2
Research Background
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are three isoforms of TGFβ (TGFβ-1, -2 and -3). TGFB2 could be a potential biomarker for screening, surveillance and prognosis in GC, and that TGFB2 might drive EMT in GC through the NGF/TrKs pathway. Overexpression of TGFB2 may drive EMT through the neuriterelated signaling and affect TMB levels by regulating the DNA damage repair pathways and immune infiltrates.TGF-β2 is an immune suppressor involvedin the development of immune tolerance, and recombinant TGF-β2 incubation is more potent than TGF-β1 or TGF-β3 incubation in suppressing macrophage inflammatory responses.
Chemical Properties
Molecular Weight13&39-50 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight