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Complement factor D-IN-2

Name: Complement factor D-IN-2
Brand: TargetMol
SKU: T38332
Price: 113 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T38332Cas No. 1903742-34-6

Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.

Complement factor D-IN-2

🥰Excellent

Purity: 99.53%

Catalog No. T38332Cas No. 1903742-34-6

Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.

Pack Size	Price	Availability
1 mg	$113	In Stock
5 mg	$268	In Stock
10 mg	$401	In Stock
25 mg	$708	In Stock
50 mg	$1,000	In Stock
100 mg	$1,300	In Stock
200 mg	$1,760	In Stock
1 mL x 10 mM (in DMSO)	$333	In Stock

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Batch Information

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Purity:99.53%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.
In vitro	Complement factor D-IN-2 mitigates the hyperactivation of complement factor D[1].

Chemical Properties

Molecular Weight	574.43
Formula	C₂₇H₂₄BrN₇O₃
Cas No.	1903742-34-6
Smiles	[H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)Nc1cccc(Br)n1)C(=O)Cn1nc(C(C)=O)c2cc(ccc12)-c1cnc(C)nc1
Relative Density.	1.67 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 70 mg/mL (121.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7409 mL	8.7043 mL	17.4086 mL	87.0428 mL
5 mM	0.3482 mL	1.7409 mL	3.4817 mL	17.4086 mL
10 mM	0.1741 mL	0.8704 mL	1.7409 mL	8.7043 mL
20 mM	0.0870 mL	0.4352 mL	0.8704 mL	4.3521 mL
50 mM	0.0348 mL	0.1741 mL	0.3482 mL	1.7409 mL
100 mM	0.0174 mL	0.0870 mL	0.1741 mL	0.8704 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc