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Complement factor D-IN-2

🥰Excellent
Catalog No. T38332Cas No. 1903742-34-6

Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.

Complement factor D-IN-2

Complement factor D-IN-2

🥰Excellent
Purity: 99.53%
Catalog No. T38332Cas No. 1903742-34-6
Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$113In StockIn Stock
5 mg$268In StockIn Stock
10 mg$401In StockIn Stock
25 mg$708In StockIn Stock
50 mg$1,000In StockIn Stock
100 mg$1,300In StockIn Stock
200 mg$1,760In StockIn Stock
1 mL x 10 mM (in DMSO)$333In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.53%
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Product Introduction

Bioactivity
Description
Complement factor D-IN-2 is an inhibitor that reduces the excessive activation of Complement factor D.
In vitro
Complement factor D-IN-2 mitigates the hyperactivation of complement factor D[1].
Chemical Properties
Molecular Weight574.43
FormulaC27H24BrN7O3
Cas No.1903742-34-6
Smiles[H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)Nc1cccc(Br)n1)C(=O)Cn1nc(C(C)=O)c2cc(ccc12)-c1cnc(C)nc1
Relative Density.1.67 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 70 mg/mL (121.86 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7409 mL8.7043 mL17.4086 mL87.0428 mL
5 mM0.3482 mL1.7409 mL3.4817 mL17.4086 mL
10 mM0.1741 mL0.8704 mL1.7409 mL8.7043 mL
20 mM0.0870 mL0.4352 mL0.8704 mL4.3521 mL
50 mM0.0348 mL0.1741 mL0.3482 mL1.7409 mL
100 mM0.0174 mL0.0870 mL0.1741 mL0.8704 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Inhibitorinhibitfactor DfactordiseasesComplementSystemComplement SystemComplement factor D-IN-2Complement factor DIN2Complement factor D IN 2complementautoimmune
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