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Synonyms: ILA17, IL-17A, IL-17, IL17, CTLA-8, CTLA8


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $88 | - | In Stock | |
| 10 μg | $136 | 7-10 days | 7-10 days | |
| 20 μg | $219 | 7-10 days | 7-10 days | |
| 50 μg | $417 | 7-10 days | 7-10 days | |
| 100 μg | $790 | 7-10 days | 7-10 days | |
| 200 μg | $1,200 | 7-10 days | 7-10 days | |
| 500 μg | $2,580 | 7-10 days | 7-10 days | |
| 1 mg | $5,280 | 7-10 days | 7-10 days |
| Bioactivity | 1. Measured by its binding ability in a functional ELISA. Immobilized IL-17A Protein, Human, Recombinant (CHO) (Cat#TMPY-07091) at 10 μg/ml (100 μl/well) can bind human IL17Ra, The EC50of human IL17Ra is 20.0-48.0 ng/mL. 2. Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.2-1 ng/mL. 3. Ixekizumab captured on Protein A chip can bind IL-17A Protein, Human, Recombinant (CHO) (Cat#TMPY-07091) with an affinity constant of 9.13 pM as determined in an SPR assay (Biacore 8K) (Routinely tested) |
| Description | IL-17A Protein, Human, Recombinant (CHO) is expressed in CHO Stable Cells. The accession number is Q16552. |
| Species | Human |
| Expression System | CHO Cells |
| Tag | Tag Free |
| Accession Number | Q16552 |
| Construction | A DNA sequence encoding the human IL17A (Q16552) (Met1-Ala155) was expressed. |
| Protein Purity | ≥ 85% as determined by SDS-PAGE, ≥ 90% as determined by SEC-HPLC, ≥ 90% as determined by SEC-MALS(Routinely tested). |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstituted with sterile deionized water to 0.1 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | ILA17, IL-17A, IL-17, IL17, CTLA-8, CTLA8 |
| Research Background |
| Molecular Weight | 15.1 kDa (predicted); 16, 19, and 20 kDa (reducing contition, due to glycosylation); 31.6 kDa (SEC-MALS) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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