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IL-17A Protein, Human, Recombinant (CHO)

(Synonyms: ILA17, IL-17A, IL-17, IL17, CTLA-8, CTLA8) Copy Product Info

Synonyms: ILA17, IL-17A, IL-17, IL17, CTLA-8, CTLA8

Catalog No. TMPY-07091 Copy Product Info
IL-17A Protein, Human, Recombinant (CHO) is expressed in CHO Stable Cells. The accession number is Q16552.
IL-17A Protein, Human, Recombinant (CHO)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$88-In Stock
10 μg$1367-10 days7-10 days
20 μg$2197-10 days7-10 days
50 μg$4177-10 days7-10 days
100 μg$7907-10 days7-10 days
200 μg$1,2007-10 days7-10 days
500 μg$2,5807-10 days7-10 days
1 mg$5,2807-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:≥ 85 % as determined by SDS-PAGE, ≥ 90 % as determined by SEC-HPLC, ≥ 90% as determined by SEC-MALS(Routinely tested).
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
1. Measured by its binding ability in a functional ELISA. Immobilized IL-17A Protein, Human, Recombinant (CHO) (Cat#TMPY-07091) at 10 μg/ml (100 μl/well) can bind human IL17Ra, The EC50of human IL17Ra is 20.0-48.0 ng/mL.
2. Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.2-1 ng/mL.
3. Ixekizumab captured on Protein A chip can bind IL-17A Protein, Human, Recombinant (CHO) (Cat#TMPY-07091) with an affinity constant of 9.13 pM as determined in an SPR assay (Biacore 8K) (Routinely tested)
Description
IL-17A Protein, Human, Recombinant (CHO) is expressed in CHO Stable Cells. The accession number is Q16552.
Species
Human
Expression System
CHO Cells
TagTag Free
Accession NumberQ16552
ConstructionA DNA sequence encoding the human IL17A (Q16552) (Met1-Ala155) was expressed.
Protein Purity
≥ 85% as determined by SDS-PAGE, ≥ 90% as determined by SEC-HPLC, ≥ 90% as determined by SEC-MALS(Routinely tested).
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
ReconstitutionReconstituted with sterile deionized water to 0.1 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsILA17, IL-17A, IL-17, IL17, CTLA-8, CTLA8
Research Background
Chemical Properties
Molecular Weight15.1 kDa (predicted); 16, 19, and 20 kDa (reducing contition, due to glycosylation); 31.6 kDa (SEC-MALS)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: IL-17A Protein, Human, Recombinant (CHO) chemical structure | IL-17A Protein, Human, Recombinant (CHO) molecular weight