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RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

Catalog No. TMPJ-00349
Synonyms: CD265 antigen, FEO, TRANCER, ODFR, ODFROSTS, TRANCE R, TNFRSF11A, OFE, OPTB7, CD265, PDB2, receptor activator of nuclear factor-κ B, RANK1, tumor necrosis factor receptor superfamily member 11A, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB

Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 110.00
50 μg 5 days $ 310.00
500 μg 5 days $ 1,300.00
1 mg 5 days $ 1,980.00
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Biological Description
Technical Params
Product Properties
Description Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number Q9Y6Q6
Synonyms CD265 antigen, FEO, TRANCER, ODFR, ODFROSTS, TRANCE R, TNFRSF11A, OFE, OPTB7, CD265, PDB2, receptor activator of nuclear factor-κ B, RANK1, tumor necrosis factor receptor superfamily member 11A, receptor activator of nuclear factor-kappa B, Receptor activator of NF-KB
Amino Acid Ile30-Pro212
Construction Recombinant Human Receptor Activator of NF-kappa-B is produced by our Mammalian expression system and the target gene encoding Ile30-Pro212 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 25-30 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutively expressed in skeletal muscle, thymus, liver, colon, small intestine, adrenal gland, osteoclast, mammary gland epithelial cells, prostate, vascular cell, and pancreas.

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Keywords

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His) CD265 antigen FEO RANK 1 TRANCER ODFR OPTB 7 ODFROSTS OPTB-7 TRANCE R PDB 2 TNFRSF11A CD 265 OFE OPTB7 CD265 PDB2 RANK-1 CD-265 receptor activator of nuclear factor-k B PDB-2 receptor activator of nuclear factor-κ B RANK1 tumor necrosis factor receptor superfamily member 11A receptor activator of nuclear factor-kappa B Receptor activator of NF-KB recombinant recombinant-proteins proteins protein

 

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