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Anti-IL-1R1 Polyclonal Antibody
(Synonyms: interleukin 1 receptor, type I) Copy Product Info
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Synonyms: interleukin 1 receptor, type I
Catalog No. TMAB-00953 Copy Product Info
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Anti-IL-1R1 Polyclonal Antibody is a Rabbit antibody targeting IL-1R1. Anti-IL-1R1 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-IL-1R1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-1R1 Polyclonal Antibody is a Rabbit antibody targeting IL-1R1. Anti-IL-1R1 Polyclonal Antibody can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | interleukin 1 receptor, type I |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Dog,Pig) |
| Application | |
| Recommended Dose | FCM=1 μg/Test; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. Cell membrane (Probable). Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II(IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human IL-1R1 |
| Antigen Species | Human |
| Gene Name | IL1R1 |
| Gene ID | |
| Protein Name | Interleukin-1 receptor type 1 |
| Uniprot ID | |
| Biology Area | Endothelial Cell Markers,Inflammatory mediators,Interleukins,T Lymphocytic Lineage,Dendritic Cell Lineage |
| Function | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. |
| Molecular Weight | Theoretical: 63 kDa. Actual: 63 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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