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Anti-IL-10R beta/IL-10RB Polyclonal Antibody is a Rabbit antibody targeting IL-10R beta/IL-10RB. Anti-IL-10R beta/IL-10RB Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-IL-10R beta/IL-10RB Polyclonal Antibody is a Rabbit antibody targeting IL-10R beta/IL-10RB. Anti-IL-10R beta/IL-10RB Polyclonal Antibody can be used in WB. |
| Synonyms | Interleukin-10 receptor subunit β(IL10RB), Interleukin-10 receptor subunit beta(IL10RB), Interleukin-10 receptor subunit 2, Cytokine receptor family 2 member 4, Cytokine receptor class-II member 4 |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | 1. Sample: Lane 1: Spleen (Rat) Lysate at 40 μg Lane 2: Lung (Rat) Lysate at 40 μg Lane 3: Small intestine (Rat) Lysate at 40 μg Lane 4: LympHnode (Rat) Lysate at 40 μg Primary: Anti-IL10RB (TMAB-00939) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kDa Observed band size: 33 kDa 2. Sample: HepG2 (Human) Cell Lysate at 30 μg Lung (Mouse) Lysate at 40 μg Lung (Rat) Lysate at 40 μg Primary: Anti-IL10RB (TMAB-00939) at 1/200 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 39 kDa Observed band size: 39 kDa ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Interleukin 10 binds specifically and with high affinity to cell surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. Mouse and human cDNA clones encoding the ligand binding IL10 receptor have been isolated. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10. |
| Immunogen | KLH conjugated synthetic peptide: human IL-10RB |
| Antigen Species | Human |
| Gene Name | IL10RB |
| Gene ID | |
| Protein Name | Interleukin-10 receptor subunit beta |
| Uniprot ID | |
| Biology Area | Interleukins,Macrophage / Inflamm.,Transmembrane |
| Molecular Weight | Theoretical: 39 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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