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Phenylpropanoids

Phenylpropanoids are a large class of plant secondary metabolites derived from aromatic amino acids phenylalanine in most plants or tyrosine in partial monocots. It mainly includes flavonoids, monolignols, phenolic acids, stilbenes, and coumarins. Phenylpropanoids are widely distributed in the plant kingdom and play vital roles in plant development by acting as essential components of cell walls, protectants against high light and UV radiation, phytoalexins against herbivores and pathogens, floral pigments to mediate plant–pollinator interactions. In addition, phenylpropanoids possess diverse biological activities that are beneficial to human health.

5-O-Caffeoylshikimic acid
TN129573263-62-4
5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.
  • $98
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Chlorogenic Acid
NSC-407296, Heriguard, 3-O-Caffeoylquinic acid
T2805327-97-9
Chlorogenic acid is a natural phenol found in honeysuckle. Chlorogenic acid has a wide range of biological activities including anti-inflammatory, antioxidant, antitumor, antimicrobial, and neuroprotective.
  • $50
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Forsythoside B
T389381525-13-5
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effects with a favorable therapeutic time
  • $33
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Myrislignan
T4S1540171485-39-5
Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induced apoptosis and cell cycle arrest
  • $39
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3,4-Dicaffeoylquinic acid
Isochlorogenic acid B
T6S152514534-61-3
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
  • $36
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Salvianolic acid A
Dan Phenolic Acid A
T6S044496574-01-5
Salvianolic acid A (Dan Phenolic Acid A) is a natural product and an inhibitor of matrix metalloproteinase 9 (MMP-9). Salvianolic acid A has antioxidant and anti-inflammatory activity and protects the blood-brain barrier.
  • $45
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Magnolol
NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol
T3000528-43-8
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
  • $39
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9'''-Methyl salvianolate B
9'''-MethyllithosperMate B
T45891167424-32-9
9'-Methyllithospermate B is a natural extract obtained from Cynoglossum columnae.
  • $38
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4,5-Dicaffeoylquinic acid
Isochlorogenic acid C, 3,4-Dicaffeoylquinic acid
T2S115857378-72-0
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.
  • $38
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Tenuifoliside A
T3856139726-35-5
Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which is mediated by the inhibition of the NF-κB and MAPK pathways.
  • $56
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2,3,4,5-Tetracaffeoyl-D-Glucaric acid
T190931419478-52-6
2,3,4,5-Tetracaffeoyl-D-Glucaric acid is a compound isolated from Inula japonica that inhibits fat accumulation and reduces body fat and can be used in the study of obesity.
  • $163
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L-DOPA
Levodopa, 3,4-Dihydroxyphenylalanine
T084859-92-7
L-DOPA (Levodopa) is an orally active metabolic precursor of the neurotransmitter dopamine. It can cross the blood-brain barrier and be converted into dopamine in the brain. L-DOPA exhibits anti-hyperalgesic effects and holds potential in Parkinson’s disease research, and it can also be used to induce Parkinson’s disease models.
  • $50
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Daphnetin
Daphnetol, 7,8-Dihydroxycoumarin
T2851486-35-1
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-inflammatory activities.
  • $43
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Magnesium Lithospermate B
T20793122021-74-3
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from ischemic injury through specific inhibition of TAB1-p38 apoptosis signaling.improves renal failure.
  • $33
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Verbascoside
TJC160, Kusaginin, Acteoside
T337561276-17-3
Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.
  • $35
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Scoparone
Scoparon, Escoparone, Aesculetin dimethyl ether, 6,7-Dimethylesculetin, 6,7-dimethoxycoumarin
T2729120-08-1
Scoparone (Aesculetin dimethyl ether) can be found in a number of food items such as sweet orange, wild celery, mandarin orange (clementine, tangerine), and lemon. It is found in the Chinese herb Artemisia scoparia and has been studied for its potential pharmacological properties including immunosuppression and vasorelaxation. Scoparone is found in anise. Scoparone is found in several citrus oils.
  • $31
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Syringin
Syringoside, Methoxyconiferine, Lilacin, eleutheroside-b
T3408118-34-3
Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.
  • $45
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Neochlorogenic acid
trans-5-O-Caffeoylquinic acid, Neochlorogenate, 5-O-Caffeoylquinic acid
T6S1538906-33-2
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.
  • $30
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Schisandrin B
Wuweizisu-B, Schizandrin B, Schisandrin B (Sch B), gamma-Schisandrin
T292561281-37-6
Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.
  • $35
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N-trans-Feruloyltyramine
N-Feruloyltyramine, Moupinamide
T3S064566648-43-9
1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-selectin expression on platelets, is a platelet aggregation inhibitor. 4. NTF inhibits melanogenesis in a dose-dependent manner, NTF induces downregulation of tyrosinase resulted in suppression of melanin biosynthesis in murine B16 melanoma cells.
  • $64
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Plantainoside D
Isoplantamajoside
T5796147331-98-4
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it also shows inhibitory activity against PKCalpha with the IC50 value14.8microM.
  • $122
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Methyl rosmarinate
TN192899353-00-1
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase. It exhibits antioxidative and antifungal activities, and also inhibits tyrosinase, α±-glucosidase, and matrix metalloproteinase-1 (MMP-1).
  • $68
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Cryptochlorogenic acid
4-O-Caffeoylquinic acid, 4-Caffeoylquinic acid
T6S1537905-99-7
1. Cryptochlorogenic acid (4-O-Caffeoylquinic acid) has antioxidant activity.
  • $34
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