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Anti-PD-1 Polyclonal Antibody
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Catalog No. TMAB-01347
Anti-PD-1 Polyclonal Antibody is a Rabbit antibody targeting PD-1. Anti-PD-1 Polyclonal Antibody can be used in FCM.
Anti-PD-1 Polyclonal Antibody
Anti-PD-1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01347
Anti-PD-1 Polyclonal Antibody is a Rabbit antibody targeting PD-1. Anti-PD-1 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Polyclonal Application: FCM Reactivity: Human,Mouse,Rat |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Blank control (blue line): Mouse spleen cells (blue). Primary Antibody (green line): Rabbit Anti-PD-1/PE-CY7 Conjugated antibody (TMAB-01347-PE-CY7) Dilution: 1 μg/10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG-PE-CY7. Protocol The cells were fixed with 70% ice-cold methanol overnight at 4°C. The cells were then incubated in 1 X PBS/2% BSA/10% goat serum to block non-specific protein-protein interactions followed by the antibody for 15 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. |
| Application | FCM |
| Recommended Dose | FCM: 1μg /test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] |
| Immunogen | KLH conjugated synthetic peptide: human PD-1 |
| Antigen Species | Human |
| Gene ID | 5133 |
| Uniprot ID | |
| Biology Area | CD,Regulatory T Cells,Death Receptors,CD markers,Apoptosis,Apoptosis |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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