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Suffruticosol A

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Catalog No. T81072Cas No. 220936-82-3

Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it partially boosts BDNF signaling and has neuromodulatory effects, leading to the restoration of memory and cognitive performance in a scopolamine-induced mouse model.

Suffruticosol A

Suffruticosol A

😃Good
Catalog No. T81072Cas No. 220936-82-3
Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it partially boosts BDNF signaling and has neuromodulatory effects, leading to the restoration of memory and cognitive performance in a scopolamine-induced mouse model.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it partially boosts BDNF signaling and has neuromodulatory effects, leading to the restoration of memory and cognitive performance in a scopolamine-induced mouse model.
In vitro
Suffruticosol A (20 μM; 24 hours) restores cell viability and survival rates in human neuroblastoma SH-SY5Y cells relative to treatment with scopolamine (2 mM) [1].
In vivo
Suffruticosol A (4 or 15 ng, biweekly; injected into the third ventricle of the brain) can ameliorate neuronal effects on cognition and memory impairments in a mouse model induced by scopolamine (1.0 mg/kg; intraperitoneal injection) [1].
Chemical Properties
Molecular Weight680.7
FormulaC42H32O9
Cas No.220936-82-3
SmilesOC=1C2=C3[C@]([C@H]([C@@H]2C4=CC(O)=CC(O)=C4)C5=CC=C(O)C=C5)([C@@H](C=6C([C@@]7(C3=C(O[C@@H]7C8=CC=C(O)C=C8)C1)[H])=CC(O)=CC6O)C9=CC=C(O)C=C9)[H]
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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