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Anti-5HT3 Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT3 Receptor. Anti-5HT3 Receptor Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-5HT3 Receptor Polyclonal Antibody is a Rabbit antibody targeting 5HT3 Receptor. Anti-5HT3 Receptor Polyclonal Antibody can be used in WB. |
Alias | Serotonin-gated ion channel receptor 3a, Serotonin receptor 3A, Serotonin receptor 3, Serotonin gated ion channel receptor, HTR-3A, HTR3, HTR 3, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3, 5-HT3R, 5HT3R, 5-HT3-A, 5-HT3A, 5HT3 serotonin receptor, 5-HT-3, 5HT3, 5HT receptor, 5HT 3A, 5HT 3, 5 hydroxytryptamine(serotonin) receptor 3A, 5 Hydroxytryptamine receptor 3, 5 HT3RA, 5 HT3A receptor, 5 HT3A, 5 HT3, 5 HT 3 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Cow) |
Verified Activity | Sample: Lane 1: Cerebellum (Mouse) Lysate at 40 μg Lane 2: Cerebrum (Mouse) Lysate at 40 μg Lane 3: Spinal cord (Mouse) Lysate at 40 μg Lane 4: Heart (Mouse) Lysate at 40 μg Lane 5: Heart (Rat) Lysate at 40 μg Primary: Anti-5-HTR3 (TMAB-00011) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52-55 kDa Observed band size: 50 kDa |
Application | WB |
Recommended Dose | WB: 1:500-2000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family. |
Immunogen | KLH conjugated synthetic peptide: human 5-HTR3 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Obesity,Serotonin Receptors,More Channels |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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