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Anti-SCGN Antibody (4D147)
😃Good
Catalog No. TMAY-02340
Alias setagin, SEGN, secretagogin, EF-hand calcium binding protein, SECRET, DJ501N12.8, CALBL
Anti-SCGN Antibody (4D147) is a Mouse antibody targeting SCGN. Anti-SCGN Antibody (4D147) can be used in IHC-P.
Anti-SCGN Antibody (4D147)
Anti-SCGN Antibody (4D147)
😃Good
Catalog No. TMAY-02340Alias setagin, SEGN, secretagogin, EF-hand calcium binding protein, SECRET, DJ501N12.8, CALBL
Anti-SCGN Antibody (4D147) is a Mouse antibody targeting SCGN. Anti-SCGN Antibody (4D147) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SCGN Antibody (4D147) is a Mouse antibody targeting SCGN. Anti-SCGN Antibody (4D147) can be used in IHC-P. |
| Alias | setagin, SEGN, secretagogin, EF-hand calcium binding protein, SECRET, DJ501N12.8, CALBL |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4D147 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human SCGN in human pancreas with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SCGN / Secretagogin (rh SCGN / Secretagogin; TMPY-01875; NP_008929.2; Asp2-Pro276). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Secretagogin, also known as SCGN, is a secreted protein that is detectable in human serum after ischemic neuronal damage. It is a recently described calcium-binding protein. Secretagogin / SCGN is expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression of Secretagogin / SCGN is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons. Secretagogin / SCGN is widely expressed in prostatic adenocarcinoma as opposed to adenocarcinomas in other organs. The function of Secretagogin / SCGN is unknown, but it has been suggested in beta-cells to influence calcium-influx and has been observed downregulated in diabetes-prone BB rat islets exposed to cytokines. Secretagogin / SCGN is involved in the calcium metabolism of tumour cells and endothelial cells in a subset of neoplasms of the brain and its coverings. Secretagogin / SCGN is also a novel marker for neuroendocrine differentiation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SCGN / Secretagogin protein (TMPY-01875) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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