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L-Palmitoylcarnitine chloride

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Catalog No. T37299Cas No. 18877-64-0
Alias Palmitoyl-L-carnitine chloride

L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).

L-Palmitoylcarnitine chloride

L-Palmitoylcarnitine chloride

😃Good
Purity: 99.96%
Catalog No. T37299Alias Palmitoyl-L-carnitine chlorideCas No. 18877-64-0
L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$35In StockIn Stock
5 mg$81In StockIn Stock
10 mg$133In StockIn Stock
25 mg$218In StockIn Stock
50 mg$325In StockIn Stock
100 mg$483-In Stock
1 mL x 10 mM (in DMSO)$89In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.96%
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Product Introduction

Bioactivity
Description
L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).
In vitro
L-Palmitoylcarnitine chloride (1-20 μM) inhibits acetylcholine- and substance P-induced endothelium-dependent relaxation in a dose-dependent manner, while having no effect on resting tension and nitroglycerin-induced relaxation[1].
In vivo
In vivo, palmitoyl-L-carnitine increases intestinal absorption of the antibiotic cefoxitin in rat intestine.
SynonymsPalmitoyl-L-carnitine chloride
Chemical Properties
Molecular Weight436.07
FormulaC23H46ClNO4
Cas No.18877-64-0
Smiles[C@H](OC(CCCCCCCCCCCCCCC)=O)(C[N+](C)(C)C)CC(O)=O.[Cl-]
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 25 mg/mL (57.33 mM), Sonication is recommended.
H2O: Slightly soluble, Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2932 mL11.4660 mL22.9321 mL114.6605 mL
5 mM0.4586 mL2.2932 mL4.5864 mL22.9321 mL
10 mM0.2293 mL1.1466 mL2.2932 mL11.4660 mL
20 mM0.1147 mL0.5733 mL1.1466 mL5.7330 mL
50 mM0.0459 mL0.2293 mL0.4586 mL2.2932 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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