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L-Palmitoylcarnitine chloride

Name: L-Palmitoylcarnitine chloride
Brand: TargetMol
SKU: T37299
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37299Cas No. 18877-64-0

Alias Palmitoyl-L-carnitine chloride

L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).

L-Palmitoylcarnitine chloride

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Purity: 99.96%

Catalog No. T37299Alias Palmitoyl-L-carnitine chlorideCas No. 18877-64-0

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$35	In Stock	In Stock
5 mg	$81	In Stock	In Stock
10 mg	$133	In Stock	In Stock
25 mg	$218	In Stock	In Stock
50 mg	$325	In Stock	In Stock
100 mg	$483	-	In Stock
1 mL x 10 mM (in DMSO)	$89	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.96%

Appearance:Solid

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).
In vitro	L-Palmitoylcarnitine chloride (1-20 μM) inhibits acetylcholine- and substance P-induced endothelium-dependent relaxation in a dose-dependent manner, while having no effect on resting tension and nitroglycerin-induced relaxation[1].
In vivo	In vivo, palmitoyl-L-carnitine increases intestinal absorption of the antibiotic cefoxitin in rat intestine.
Synonyms	Palmitoyl-L-carnitine chloride

Chemical Properties

Molecular Weight	436.07
Formula	C₂₃H₄₆ClNO₄
Cas No.	18877-64-0
Smiles	[C@H](OC(CCCCCCCCCCCCCCC)=O)(C[N+](C)(C)C)CC(O)=O.[Cl-]
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25 mg/mL (57.33 mM), Sonication is recommended.

H2O: Slightly soluble, Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2932 mL	11.4660 mL	22.9321 mL	114.6605 mL
5 mM	0.4586 mL	2.2932 mL	4.5864 mL	22.9321 mL
10 mM	0.2293 mL	1.1466 mL	2.2932 mL	11.4660 mL
20 mM	0.1147 mL	0.5733 mL	1.1466 mL	5.7330 mL
50 mM	0.0459 mL	0.2293 mL	0.4586 mL	2.2932 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc