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Timosaponin A1

Name: Timosaponin A1
Brand: TargetMol
SKU: T2S2295
Price: 54 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2S2295Cas No. 68422-00-4

Timosaponin A1, a coprostane-type steroidal saponin, is found in Rhizoma Anemarrhenae.

Timosaponin A1

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Purity: 99.59%

Catalog No. T2S2295Cas No. 68422-00-4

Timosaponin A1, a coprostane-type steroidal saponin, is found in Rhizoma Anemarrhenae.

Pack Size	Price	Availability
1 mg	$54	In Stock
2 mg	$77	In Stock
5 mg	$128	In Stock
10 mg	$193	In Stock
25 mg	$326	In Stock
50 mg	$486	In Stock
1 mL x 10 mM (in DMSO)	$167	In Stock

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Purity:99.59%

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COA

Product Introduction

Bioactivity

Description	Timosaponin A1, a coprostane-type steroidal saponin, is found in Rhizoma Anemarrhenae.
Targets&IC50	DPP-4:33.25 μM, COX-2:36.43 μM, 5-LOX:3.29 μM
In vitro	timosaponin AI inhibited DPP-4 activity at the concentration of 5-50 μmol?L?1 in a dose-dependent manner.

Chemical Properties

Molecular Weight	578.78
Formula	C₃₃H₅₄O₈
Cas No.	68422-00-4
Smiles	[H][C@]12C[C@@]3([H])[C@]4([H])CC[C@]5([H])C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Relative Density.	1.26 g/cm3 at 20℃
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 9 mg/mL (15.55 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7278 mL	8.6389 mL	17.2777 mL	86.3886 mL
5 mM	0.3456 mL	1.7278 mL	3.4555 mL	17.2777 mL
10 mM	0.1728 mL	0.8639 mL	1.7278 mL	8.6389 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc