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Timosaponin A1

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Catalog No. T2S2295Cas No. 68422-00-4

Timosaponin A1, a coprostane-type steroidal saponin, is found in Rhizoma Anemarrhenae.

Timosaponin A1

Timosaponin A1

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Purity: 99.59%
Catalog No. T2S2295Cas No. 68422-00-4
Timosaponin A1, a coprostane-type steroidal saponin, is found in Rhizoma Anemarrhenae.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$54In StockIn Stock
2 mg$77In StockIn Stock
5 mg$128In StockIn Stock
10 mg$193In StockIn Stock
25 mg$326In StockIn Stock
50 mg$486In StockIn Stock
1 mL x 10 mM (in DMSO)$167In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.59%
Color:White
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Product Introduction

Bioactivity
Description
Timosaponin A1, a coprostane-type steroidal saponin, is found in Rhizoma Anemarrhenae.
Targets&IC50
5-LOX:3.29 μM, COX-2:36.43 μM, DPP4:33.25 μM
In vitro
timosaponin AI inhibited DPP-4 activity at the concentration of 5-50 μmol?L?1 in a dose-dependent manner.
Chemical Properties
Molecular Weight578.78
FormulaC33H54O8
Cas No.68422-00-4
Smiles[H][C@]12C[C@@]3([H])[C@]4([H])CC[C@]5([H])C[C@H](CC[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CC[C@H](C)CO1)O2)O[C@]1([H])O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
Relative Density.1.26 g/cm3 at 20℃
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 9 mg/mL (15.55 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7278 mL8.6389 mL17.2777 mL86.3886 mL
5 mM0.3456 mL1.7278 mL3.4555 mL17.2777 mL
10 mM0.1728 mL0.8639 mL1.7278 mL8.6389 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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