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Anti-CD20 Antibody-PerCP (8W940) is a PerCP-conjugated Rabbit antibody targeting CD20. Anti-CD20 Antibody-PerCP (8W940) can be used in FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 T | $105 | 7-10 days | |
100 T | $328 | 7-10 days |
Description | Anti-CD20 Antibody-PerCP (8W940) is a PerCP-conjugated Rabbit antibody targeting CD20. Anti-CD20 Antibody-PerCP (8W940) can be used in FCM. |
Alias | S7, MS4A2, MS4A1, membrane-spanning 4-domains, subfamily A, member 1, LEU-16, CVID5, CD20, Bp35, B1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8W940 |
Reactivity | Human |
Verified Activity | Profile of anti-CD20 reactivity on peripheral blood lymphocytes analyzed by flow cytometry. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, Human CD20 Transfected CHO Cells and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed in all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections, and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells are usually in the normal range but can be very low.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | PerCP |
Others Formats | Unconjugated/APC/FITC/PE |
Antibody Types Available | 5 |
Immunogen | Human CD20 Transfected CHO Cells |
Antigen Species | Human |
Biology Area | Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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