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Collagenase Type I
🥰Excellent
Catalog No. T64812
Alias Collagenase Type I (From microorganisms), Collagenase I, 9001-12-1
Collagenase Type I is a proteolytic enzyme that primarily targets collagen and is able to break down peptide bonds in collagen. Collagenase is used as a potential therapeutic option to break up the herniated disc material, thereby reducing compression of nearby nerves. Collagenase may aid in the breakdown and reorganization of excessive scar tissue, potentially improving tissue function and appearance. Collagenase has the potential to treat intervertebral disc herniation, keloid, fat mass, lipoma, as well as Peyronie's disease and palmar fibromatosis.
Collagenase Type I
Collagenase Type I
🥰Excellent
Catalog No. T64812Alias Collagenase Type I (From microorganisms), Collagenase I, 9001-12-1
Collagenase Type I is a proteolytic enzyme that primarily targets collagen and is able to break down peptide bonds in collagen. Collagenase is used as a potential therapeutic option to break up the herniated disc material, thereby reducing compression of nearby nerves. Collagenase may aid in the breakdown and reorganization of excessive scar tissue, potentially improving tissue function and appearance. Collagenase has the potential to treat intervertebral disc herniation, keloid, fat mass, lipoma, as well as Peyronie's disease and palmar fibromatosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $39 | In Stock | |
| 100 mg | $55 | In Stock |
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Potency:>125CDU/mg
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Chemical Properties
| Description | Collagenase Type I is a proteolytic enzyme that primarily targets collagen and is able to break down peptide bonds in collagen. Collagenase is used as a potential therapeutic option to break up the herniated disc material, thereby reducing compression of nearby nerves. Collagenase may aid in the breakdown and reorganization of excessive scar tissue, potentially improving tissue function and appearance. Collagenase has the potential to treat intervertebral disc herniation, keloid, fat mass, lipoma, as well as Peyronie's disease and palmar fibromatosis. |
| In vivo | METHODS: To investigate the effect of Collagenase Type II (similar to Collagenase Type I) on the cornea, the corneas of New Zealand white rabbits were treated with Collagenase Type II (200 μL at 5 mg/mL) for 30 minutes. RESULTS: Collagenase Type I increases the curvature and thinning of the cornea and reduces the elastic modulus, thereby simulating the pathological characteristics of Keratoconus (KC). [1] |
| Synonyms | Collagenase Type I (From microorganisms), Collagenase I, 9001-12-1 |
Storage & Solubility Information
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 50 mg/mL, Sonication is recommended.  |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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