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Anti-BMP-4 Polyclonal Antibody
(Synonyms: ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B) Copy Product Info
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Synonyms: ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Catalog No. TMAB-00243 Copy Product Info
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Anti-BMP-4 Polyclonal Antibody is a Rabbit antibody targeting BMP-4. Anti-BMP-4 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-BMP-4 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-BMP-4 Polyclonal Antibody is a Rabbit antibody targeting BMP-4. Anti-BMP-4 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B |
| Ig Type | IgG |
| Reactivity | Mouse,Sheep (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix. |
| Immunogen | KLH conjugated synthetic peptide: human BMP4 |
| Antigen Species | Human |
| Gene Name | BMP4 |
| Gene ID | |
| Protein Name | Bone morphogenetic protein 4 |
| Uniprot ID | |
| Biology Area | TGF,TGF,Kidney development,Gut specification,Nervous system development,TGF,Secreted |
| Function | Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. |
| Molecular Weight | Theoretical: 13/45 kDa. Actual: 50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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