GPRC5D Protein-VLP, Human, Recombinant

Catalog No. TMPY-06494

GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1.

GPRC5D Protein-VLP, Human, Recombinant

Catalog No. TMPY-06494

GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1.

Pack Size	Price	Availability
5 μg	$298	7-10 days
10 μg	$490	7-10 days
20 μg	$838	7-10 days
50 μg	$1,230	7-10 days
100 μg	$1,930	7-10 days
200 μg	$2,750	7-10 days
500 μg	$6,150	7-10 days

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Product Information

Biological Activity	Immobilized Human GPRC5D-VLP (Full Length) Protein at 5 μg/mL (100 μL/well) can bind anti-GPRC5D Antibody, the EC50 is 3-10 ng/mL.
Description	GPRC5D Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.80 kDa and the accession number is Q9NZD1-1.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	Q9NZD1-1
Synonyms	GPRC5D
Construction	A DNA sequence encoding the human GPRC5D (Q9NZD1-1) (Met1-Val345) was expressed. Predicted N terminal: Met 1
Molecular Weight	38.80 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile solution in 50 mM HEPES, 150 mM NaCI, 10% Trehalose, pH 7.2.
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Shipping with blue ice.
Research Background	Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.