LYVE1 Protein, Human, Recombinant (His)

Name: LYVE1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00533
Rating: 4.5 (1 reviews)

(Synonyms: XLKD1, LYVE-1, LYVE1, Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Hyaluronic Acid Receptor, HAR, Extracellular Link Domain-Containing Protein 1, CRSBP-1, CRSBP1, Cell Surface Retention Sequence-Binding Protein 1) Copy Product Info

Synonyms: XLKD1, LYVE-1, LYVE1, Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Hyaluronic Acid Receptor, HAR, Extracellular Link Domain-Containing Protein 1, CRSBP-1, CRSBP1, Cell Surface Retention Sequence-Binding Protein 1

Catalog No. TMPJ-00533 Copy Product Info

Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Pack Size	Price	USA Stock	Global Stock
5 µg	$88	7-10 days	7-10 days
10 µg	$143	7-10 days	7-10 days
20 µg	$229	7-10 days	7-10 days
50 µg	$433	7-10 days	7-10 days
100 µg	$675	7-10 days	7-10 days
200 µg	$1,050	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 99.9%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	AAH26231.1
Amino Acid	Leu20-Thr238
Construction	Leu20-Thr238
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-Citrate, 150 mM NaCl, pH 7.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	XLKD1, LYVE-1, LYVE1, Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Hyaluronic Acid Receptor, HAR, Extracellular Link Domain-Containing Protein 1, CRSBP-1, CRSBP1, Cell Surface Retention Sequence-Binding Protein 1
Research Background	Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

Chemical Properties

Molecular Weight

46 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.