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LYVE1 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00533
Synonyms: XLKD1, Cell Surface Retention Sequence-Binding Protein 1, Extracellular Link Domain-Containing Protein 1, HAR, CRSBP-1, CRSBP1, Hyaluronic Acid Receptor, LYVE-1, LYVE1, Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1

Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
LYVE1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 143.00
50 μg 5 days $ 434.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number AAH26231.1
Synonyms XLKD1, Cell Surface Retention Sequence-Binding Protein 1, Extracellular Link Domain-Containing Protein 1, HAR, CRSBP-1, CRSBP1, Hyaluronic Acid Receptor, LYVE-1, LYVE1, Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1
Amino Acid Leu20-Thr238
Construction Recombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Thr238 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 46 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-Citrate, 150mM NaCl, pH 7.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

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Keywords

LYVE1 Protein, Human, Recombinant (His) XLKD1 XLKD-1 XLKD 1 Cell Surface Retention Sequence-Binding Protein 1 Extracellular Link Domain-Containing Protein 1 HAR CRSBP-1 CRSBP1 LYVE 1 CRSBP 1 Hyaluronic Acid Receptor LYVE-1 LYVE1 Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 recombinant recombinant-proteins proteins protein

 

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