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Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)

Catalog No. TMPH-00343
Synonyms: Angiopoietin-1, ANG-1, ANGPT1

Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.

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Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 614.00
100 μg 20 days $ 1,720.00
1 mg 20 days $ 7,240.00
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Biological Description
Technical Params
Product Properties
Description Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.
Species Canine
Expression System HEK293
Tag C-terminal 6xHis-tagged
Accession Number Q60FC1
Synonyms Angiopoietin-1, ANG-1, ANGPT1
Amino Acid SNQRRSPENGGRRYNRIQHGQCAYTFILPEHDGNCRESTTDQYNTNALQRDAPHVGPDFSSQKLQHLEHVMENYTQWLQKIENYIVENMKSEMAQIQQNAVQNHTATMLEIGTSLLSQTAEQTRKLTDVETQVLNQTSRLEIQLLENSLSTYKLEKQLLQQTNEILKIHEKNSLLEHKILEMEGKHKEEWDTLKEERENLQVLVTRQTYIIQELEKQLNRATNNNSVLQKQQLELMDTVHNLVNLCTKEVLLKGGKKEEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQHREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYTLRIELMDCEGNRAYSQYDRFHIGNEKQNYRLYLKCHTGTAGKQSSLILHGADFSTKDADNDNCMCKCALMLTGGWWFDACGPSNLNGMFYTAGQNHGKLNGIKWHYFKGPSYSLRSTTMMIRPLDF Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 20-497 aa
Protein Purity > 85% as determined by SDS-PAGE.
Molecular Weight 58.8 kDa as predicted
Formulation If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development.

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Keywords

Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) Angiopoietin-1 ANG-1 ANGPT1 recombinant recombinant-proteins proteins protein

 

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