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Synonyms: Tyro4, Mek4, Hek4, Hek, ETK1, EPH receptor A3, End3, Cek4, AW492086

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $152 | 7-10 days | 7-10 days | |
| 20 µg | $248 | 7-10 days | 7-10 days | |
| 50 µg | $577 | 7-10 days | 7-10 days |
| Bioactivity | Kinase activity untested |
| Description | EphA3 Protein, Mouse, Recombinant (aa 569-984) is expressed in Baculovirus insect cells. The predicted molecular weight is 46.6 kDa and the accession number is EDK98238.1. |
| Species | Mouse |
| Expression System | Baculovirus Insect Cells |
| Tag | Tag Free |
| Accession Number | EDK98238.1 |
| Construction | A DNA sequence encoding the mouse EPHA3 (EDK98238.1) (Gly569-Val984) was expressed with two additional amino acids (Gly & Pro ) at the N-terminus. Predicted N terminal: Gly |
| Protein Purity | > 85 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 8.0. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Synonyms | Tyro4, Mek4, Hek4, Hek, ETK1, EPH receptor A3, End3, Cek4, AW492086 |
| Research Background | EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Molecular Weight | 46.6 kDa (predicted); 44 kDa (reducing conditions) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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