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Synonyms: Retinol Dehydrogenase, Gastric Alcohol Dehydrogenase, Alcohol Dehydrogenase Class IV μ/σ Chain, Alcohol Dehydrogenase Class IV Mu/Sigma Chain, Alcohol Dehydrogenase Class 4 μ/σ Chain, Alcohol Dehydrogenase Class 4 Mu/Sigma Chain, ADH7


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $112 | 35 days | 35 days | |
| 10 µg | $183 | 35 days | 35 days | |
| 20 µg | $292 | 35 days | 35 days | |
| 50 µg | $545 | 35 days | 35 days | |
| 100 µg | $792 | 35 days | 35 days | |
| 200 µg | $1,150 | 35 days | 35 days | |
| 500 µg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,730 | 35 days | 35 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | P40394 |
| Amino Acid | Met1-Phe386 |
| Construction | Met1-Phe386 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | Retinol Dehydrogenase, Gastric Alcohol Dehydrogenase, Alcohol Dehydrogenase Class IV μ/σ Chain, Alcohol Dehydrogenase Class IV Mu/Sigma Chain, Alcohol Dehydrogenase Class 4 μ/σ Chain, Alcohol Dehydrogenase Class 4 Mu/Sigma Chain, ADH7 |
| Research Background | Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism. |
| Molecular Weight | 44 KDa (reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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