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ADH7 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00953
Synonyms: Retinol Dehydrogenase, Alcohol Dehydrogenase Class 4 μ/σ Chain, Alcohol Dehydrogenase Class IV Mu/Sigma Chain, ADH7, Gastric Alcohol Dehydrogenase, Alcohol Dehydrogenase Class IV μ/σ Chain, Alcohol Dehydrogenase Class 4 Mu/Sigma Chain

Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.

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ADH7 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number P40394
Synonyms Retinol Dehydrogenase, Alcohol Dehydrogenase Class 4 μ/σ Chain, Alcohol Dehydrogenase Class IV Mu/Sigma Chain, ADH7, Gastric Alcohol Dehydrogenase, Alcohol Dehydrogenase Class IV μ/σ Chain, Alcohol Dehydrogenase Class 4 Mu/Sigma Chain
Amino Acid Met1-Phe386
Construction Recombinant Human Alcohol Dehydrogenase Class 4 Mu/Sigma Chain is produced by our Mammalian expression system and the target gene encoding Met1-Phe386 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 44 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Alcohol dehydrogenase class 4 mu/sigma chain (ADH7) is a cytoplasm enzyme which is a member of the alcohol dehydrogenase family. The expression of this gene makes it much more abundant in the stomach than the liver, thus it differs from the other known gene family members. ADH7 may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.

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Keywords

ADH7 Protein, Human, Recombinant (His) ADH-7 Retinol Dehydrogenase Alcohol Dehydrogenase Class 4 μ/σ Chain Alcohol Dehydrogenase Class 4 Mu/σ Chain Alcohol Dehydrogenase Class IV Mu/Sigma Chain ADH7 Gastric Alcohol Dehydrogenase Alcohol Dehydrogenase Class IV Mu/σ Chain ADH 7 Alcohol Dehydrogenase Class IV μ/σ Chain Alcohol Dehydrogenase Class 4 Mu/Sigma Chain recombinant recombinant-proteins proteins protein

 

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