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Anti-RNF43 Polyclonal Antibody
😃Good
Catalog No. TMAB-01625
Alias URCC, RNF43, RNF124, ring finger protein 43
Anti-RNF43 Polyclonal Antibody is a Rabbit antibody targeting RNF43. Anti-RNF43 Polyclonal Antibody can be used in WB.
Anti-RNF43 Polyclonal Antibody
Anti-RNF43 Polyclonal Antibody
😃Good
Catalog No. TMAB-01625Alias URCC, RNF43, RNF124, ring finger protein 43
Anti-RNF43 Polyclonal Antibody is a Rabbit antibody targeting RNF43. Anti-RNF43 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-RNF43 Polyclonal Antibody is a Rabbit antibody targeting RNF43. Anti-RNF43 Polyclonal Antibody can be used in WB. |
| Synonyms | URCC, RNF43, RNF124, ring finger protein 43 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse) |
| Verified Activity | Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Pancreas tissue lysates Lane 3: Mouse Lung tissue lysates Lane 4: Mouse Heart tissue lysates Lane 5: Human 293T cell lysates Lane 6: Human HepG2 cell lysates Lane 7: Human A549 cell lysates Lane 8: Human HL-60 cell lysates Primary: Anti-RNF43 (TMAB-01625) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 83 kDa Observed band size: 110 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Nucleus envelope. |
| Tissue Specificity | Expressed in fetal kidney, fetal lung, in colon cancer tissues, hepatocellular carcinomas and lung adenocarcinomas. Overexpressed in colorectal cancer cell lines. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | RNF43 is a probable E3 ubiquitin-protein ligase that promotes cell growth and is upregulated in colon cancer. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Immunogen | KLH conjugated synthetic peptide: human RNF43 |
| Antigen Species | Human |
| Gene Name | RNF43 |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase RNF43 |
| Uniprot ID | |
| Biology Area | Oncoproteins,Tumor antigens,Tumor-associated antigens,RING Finger E3 Ligase |
| Function | Probable E3 ubiquitin-protein ligase. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| Molecular Weight | Theoretical: 83 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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