Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pim-1 kinase inhibitor 1 can be used in cancer research, showing anticancer activity against a variety of cancer cell lines by promoting cell apoptosis. Pim-1 kinase inhibitor 1 is an inhibitor of Pim-1 kinase with an IC 50 value of 0.11 μM [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Pim-1 kinase inhibitor 1 can be used in cancer research, showing anticancer activity against a variety of cancer cell lines by promoting cell apoptosis. Pim-1 kinase inhibitor 1 is an inhibitor of Pim-1 kinase with an IC 50 value of 0.11 μM [1]. |
In vitro | Pim-1 kinase inhibitor 1, within a concentration range of 0-200 μM over a 24-hour incubation period, exhibits significant in vitro cytotoxicity against various cancer cell lines, including MCF-7, CACO, HepG-2, HCT-116, and WI-38, demonstrating its potential anti-cancer activity. The compound not only showed cytotoxic effects with IC50 values of 10.93, 4.91, 7.01, 3.41, and 27.181 μM for the respective cell lines but also promoted apoptosis through the upregulation of Casp-3, BAX, and Bcl-2 proteins. |
Molecular Weight | 331.32 |
Formula | C19H13N3O3 |
CAS No. | 2803505-57-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pim-1 kinase inhibitor 1 2803505-57-7 inhibitor inhibit