Shopping Cart
- Remove All
Your shopping cart is currently empty
(2)
PROTACMolecular Glues
Molecular glue refers to a class of chemical compounds or molecules that play a crucial role in binding and stabilizing protein-protein interactions in biological systems. These molecules act as "glue" by enhancing the affinity between proteins, ultimately influencing various cellular processes. Molecular glue compounds have gained significant attention in the fields of drug discovery, chemical biology, and fundamental research due to their potential to modulate protein interactions, and thus, impact various cellular pathways. They have unlocked avenues in medicine previously thought to be “undruggable.”
- MezigdomideT107032259648-80-9In houseMezigdomide (CC-92480) is a potent, novel, selective and active cereblon E3 ubiquitin ligase modulator (CELMoD) that often acts as a molecular glue. Mezigdomide has antimyeloma activity.
- $118
SizeQTY
- LenalidomideT1642191732-72-6Lenalidomide (CC-5013) is an immunomodulator with oral activity. Lenalidomide is a ligand for the ubiquitin E3 ligase cereblon (CRBN), which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase, and is commonly used in the synthesis of PROTAC products.
- $36
SizeQTY
Cited - PomalidomideT238419171-19-8Pomalidomide (CC-4047) is an anti-angiogenic and immunomodulatory agent. Pomalidomide is a ligand for the ubiquitin E3 ligase cereblon (CRBN) and is commonly used in the synthesis of PROTAC products.
- $52
SizeQTY Cited - EragidomideT107651860875-51-9Dicyclanil is an insect growth regulator with a chemical structure similar to that of cyclopromazine.
- $34
SizeQTY - ThalidomideT021350-35-1Thalidomide (Thalomid) is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties.
- $50
SizeQTY Cited - FPFT-2216T606082367619-87-0FPFT-2216 is a molecular gel that degrades IKZF6, IKZF1, DE1D, and CK3α.FPFT-2216 has potential antitumor activity and can be used to study diseases of the immune system.FPFT-2216 is a molecular gel that degrades IKZF6, IKZF1, DE1D, and CK3α.
- $98
SizeQTY - dCeMM2T61477296771-07-8dCeMM2 is a glue degrader. dCeMM2 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, leading to the ubiquitination and degradation of cyclin K.
- $31
SizeQTY - HQ461T98491226443-41-9HQ461 is a molecular glue that promotes CDK12-DDB1 interaction, triggering cyclin K degradation, decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.
- $38
SizeQTY
- dCeMM1T67778118719-16-7dCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells.
- $32
SizeQTY - Lenalidomide hemihydrateT22922847871-99-2Lenalidomide hemihydrate is a derivative of Thalidomide, an orally active immunomodulator that acts as a molecular gel. It is a ligand for the ubiquitin E3 ligase cereblon, which selectively ubiquitinates and degrades two lymphoid transcription factors, IKZF1 and IKZF3, via the CRBN-CRL4 ubiquitin ligase.
- $29
SizeQTY - Antitumor agent-100 hydrochlorideT791382841750-53-4Antitumor agent-100 hydrochloride (compound A6), serving as both an apoptosis inducer and molecular glue, exhibits superior anti-tumor activity [1].
- Inquiry Price
SizeQTY - Naphthyridine carbamate dimerT81705864627-58-7Naphthyridine carbamate dimer (NCD) acts as a molecular glue for DNA, facilitating specific structural alterations within targeted functional DNA sequences to modulate their activity [1].
- Inquiry Price
SizeQTY
Go to page 1
Page of 1
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.