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Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603)
😃Good
Catalog No. TMAB-01660
Alias Surface glycoprotein, SPIKE_SARS2, Spike protein S1, Spike protein RBD, Spike glycoprotein, SARS-CoV-2 spike protein, 2019-nCOV Spike protein
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) is a Mouse antibody targeting SARS-CoV-2 (2019-nCoV) Spike Neutralizing. Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) can be used in ELISA.
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603)
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603)
😃Good
Catalog No. TMAB-01660Alias Surface glycoprotein, SPIKE_SARS2, Spike protein S1, Spike protein RBD, Spike glycoprotein, SARS-CoV-2 spike protein, 2019-nCOV Spike protein
Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) is a Mouse antibody targeting SARS-CoV-2 (2019-nCoV) Spike Neutralizing. Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $679 | 7-10 days |
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| Description | Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) is a Mouse antibody targeting SARS-CoV-2 (2019-nCoV) Spike Neutralizing. Anti-SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody (7D603) can be used in ELISA. |
| Alias | Surface glycoprotein, SPIKE_SARS2, Spike protein S1, Spike protein RBD, Spike glycoprotein, SARS-CoV-2 spike protein, 2019-nCOV Spike protein |
| Ig Type | IgG1 |
| Clone | 7D603 |
| Reactivity | Virus |
| Verified Activity | 1. The ACE2-coated plate is incubated with SARS-CoV-2 Spike RBD-HRP (WT) and Anti-SARS-CoV-2 Spike RBD Neutralizing antibody. Percent inhibition is calculated based on the OD value by inhibiting RBD: ACE2 interaction. 2. Direct ELISA was used to detect the binding ability of anti-RBD monoclonal antibody to RBD domain proteins of different SARS-CoV-2 Mutant Strains. Immobilized SARS-CoV-2 RBD proteins, at 2 μg/ml (100ul/Well) can bind Anti-RBD monoclonal antibody-HRP at 1 μg/ml (100ul/Well). |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-10000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Virion membrane ; Single-pass type I membrane protein ; Host endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass type I membrane protein ; Host cell membrane ; Single-pass type I membrane protein ;Note: Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Colocalizes with S in the host endoplasmic reticulum-Golgi intermediate compartment. Some S oligomers are transported to the host plasma membrane, where they may mediate cell-cell fusion. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4). |
| Research Background | The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic, and are now the dominant form worldwide. Here, we analyze the D614G mutation in the context of a soluble S ectodomain construct. |
| Immunogen | Recombinant Protein: SARS-CoV-2 Spike S1 Protein |
| Biology Area | SARS Coronavirus |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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