SOX-2 Protein, Mouse, Recombinant (His)

Name: SOX-2 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-07226
Price: 942 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: ysb, Sox-2, lcc) Copy Product Info

Synonyms: ysb, Sox-2, lcc

Catalog No. TMPY-07226 Copy Product Info

SOX-2 Protein, Mouse, Recombinant (His) is expressed in E. coli. The accession number is P48432.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$128	-	In Stock
10 µg	$205	-	In Stock
20 µg	$327	7-10 days	7-10 days
50 µg	$589	7-10 days	7-10 days
100 µg	$942	7-10 days	7-10 days
200 µg	Inquiry	7-10 days	7-10 days
500 µg	Inquiry	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:≥ 75 % as determined by SDS-PAGE.

Appearance:Solution

Color:Transparent

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SOX-2 Protein, Mouse, Recombinant (His) is expressed in E. coli. The accession number is P48432.
Species	Mouse
Expression System	E. coli
Tag	N-His
Accession Number	P48432
Construction	A DNA sequence encoding the Mouse SOX2 (P48432) (Met1-Met319) was expressed, with a polyhistidine tag at the N-terminus.
Protein Purity	≥ 75 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 20 mM Tris, 500 mM NaCl, 2M Urea, 1mM EDTA, 1mM TCEP, pH 7.4. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Synonyms	ysb, Sox-2, lcc
Research Background	SOX2 is a member of the SOXB1 subfamily of transcription factors most notably involved in the reprogramming of somatic cells into induced pluripotent stem cells. Housed on chromosome 3, the SOX2 gene encodes for a protein with a C-terminal transcriptional activation domain and a DNA-binding HMG domain that contains a nuclear localization/export signal. SOX2 forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development and pluripotency such as YES1, FGF4, UTF1 and ZFP206. Mutations in this gene have been associated with bilateral eye disease. SOX2 antigen and antibody were found in small-cell lung cancer cell lines and sera. However, neither exists in normal sera, suggesting that SOX2 might be a potential tumor target or marker.

Chemical Properties

Molecular Weight

35.42 kDa (predicted)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.