FGF-7/KGF Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

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Catalog No. TMPK-00081

The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.

FGF-7/KGF Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

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Catalog No. TMPK-00081

Pack Size	Price	USA Warehouse	Global Warehouse
5 μg	$98	7-10 days	7-10 days
10 μg	$168	7-10 days	7-10 days
20 μg	$279	7-10 days	7-10 days
50 μg	$552	7-10 days	7-10 days
100 μg	$932	7-10 days	7-10 days
200 μg	$1,680	7-10 days	7-10 days
500 μg	$3,720	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Information

Biological Activity	Immobilized Human FGFR2 beta (IIIb), hFc Tag at 5 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Human FGF-7, His Tag with the EC50 of 0.14 μg/mL determined by ELISA (QC Test). Human FGFR2 beta (IIIb), hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated Human FGF-7, His Tag with an affinity constant of 0.74 nM as determined in SPR assay (Biacore T200).
Description	The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.
Species	Human
Expression System	E. coli
Tag	N-His
Accession Number	P21781-1
Synonyms	KGF,HBGF-7,FGF-7
Construction	Cys32-Thr194
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	20.1 kDa (predicted) same as Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in 50 mM Tris, 250 mM NaCl (pH 7.5).
Stability & Storage	It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	Proteins are shipped with blue ice.
Research Background	The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.