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Anti-ATP1A1 Antibody (5G770) is a Mouse antibody targeting ATP1A1. Anti-ATP1A1 Antibody (5G770) can be used in WB,IP,IF,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $497 | 7-10 days |
Description | Anti-ATP1A1 Antibody (5G770) is a Mouse antibody targeting ATP1A1. Anti-ATP1A1 Antibody (5G770) can be used in WB,IP,IF,IHC-P. |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | WB: 1:2000-10000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase. |
Conjucates | Unconjugated |
Immunogen | Amino acids 551-850 of Na+/K+-ATPase α1 of human origin |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 100-143 kDa. |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
Transport | Shipping with blue ice. |
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