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UBE2S Protein, Human, Recombinant (GST)
(Synonyms: Ubiquitin-Protein Ligase S, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2 S, Ubiquitin Carrier Protein S, UBE2S, E2-EPF, E2EPF) Copy Product InfoSynonyms: Ubiquitin-Protein Ligase S, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2 S, Ubiquitin Carrier Protein S, UBE2S, E2-EPF, E2EPF
Catalog No. TMPJ-01138 Copy Product Info
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 μg | $35 | 7-10 days | 7-10 days | |
| 20 μg | $53 | 7-10 days | 7-10 days | |
| 50 μg | $97 | 7-10 days | 7-10 days | |
| 100 μg | $148 | 7-10 days | 7-10 days | |
| 200 μg | $236 | 7-10 days | 7-10 days | |
| 500 μg | $433 | 7-10 days | 7-10 days | |
| 1 mg | $621 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-GST |
| Accession Number | Q16763 |
| Amino Acid | Met1-Leu222 |
| Construction | Met1-Leu222 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Ubiquitin-Protein Ligase S, Ubiquitin-Conjugating Enzyme E2-EPF5, Ubiquitin-Conjugating Enzyme E2-24 kDa, Ubiquitin-Conjugating Enzyme E2 S, Ubiquitin Carrier Protein S, UBE2S, E2-EPF, E2EPF |
| Research Background |
| Molecular Weight | 50 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: UBE2S Protein, Human, Recombinant (GST) chemical structure | UBE2S Protein, Human, Recombinant (GST) molecular weight
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