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AMP-PNP lithium hydrate is a non-hydrolyzable ATP analog. It can substitute for ATP in biological research and is not hydrolyzed by intracellular enzymes. In a study on the vitamin B12 transporter BtuCD-F, AMP-PNP was found to block the channels formed by the two BtuCD components of the BtuCD-F complex, thereby preventing the entry of vitamin B12.
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Description | AMP-PNP lithium hydrate is a non-hydrolyzable ATP analog. It can substitute for ATP in biological research and is not hydrolyzed by intracellular enzymes. In a study on the vitamin B12 transporter BtuCD-F, AMP-PNP was found to block the channels formed by the two BtuCD components of the BtuCD-F complex, thereby preventing the entry of vitamin B12. |
Synonyms | AMP-PNP lithium hydrate, Adenylyl imidodiphosphate lithium hydrate |
Formula | C10H17N6O12P3.xLi.xH2O |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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