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Pergolide mesylate

Name: Pergolide mesylate
Brand: TargetMol
SKU: T2226
Price: 47 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2226Cas No. 66104-23-2

Alias Pergolide methanesulfonate, Pergolide mesylate salt, LY127809

Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.

Pergolide mesylate

🥰Excellent

Purity: 99.70%

Catalog No. T2226Alias Pergolide methanesulfonate, Pergolide mesylate salt, LY127809Cas No. 66104-23-2

Pack Size	Price	Availability
5 mg	$47	In Stock
10 mg	$67	In Stock
25 mg	$117	In Stock
50 mg	$187	In Stock
1 mL x 10 mM (in DMSO)	$52	In Stock

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Batch Information

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Purity:99.70%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES.
Synonyms	Pergolide methanesulfonate, Pergolide mesylate salt, LY127809

Chemical Properties

Molecular Weight	410.59
Formula	C₂₀H₃₀N₂O₃S₂
Cas No.	66104-23-2
Smiles	CS(O)(=O)=O.CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (133.95 mM), Sonication is recommended.

H2O: 40 mg/mL (97.4 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4355 mL	12.1776 mL	24.3552 mL	121.7760 mL
5 mM	0.4871 mL	2.4355 mL	4.8710 mL	24.3552 mL
10 mM	0.2436 mL	1.2178 mL	2.4355 mL	12.1776 mL
20 mM	0.1218 mL	0.6089 mL	1.2178 mL	6.0888 mL
50 mM	0.0487 mL	0.2436 mL	0.4871 mL	2.4355 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0244 mL	0.1218 mL	0.2436 mL	1.2178 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc