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Methyltetrazine-PEG5-methyltetrazine

🥰Excellent
Catalog No. T18353

Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used to synthesise PROTAC molecules. Methyltetrazine-PEG5-methyltetrazine contains a Tetrazine moiety, which can be used in an iEDDA click chemistry reaction with molecules containing TCO moiety.

Methyltetrazine-PEG5-methyltetrazine

Methyltetrazine-PEG5-methyltetrazine

🥰Excellent
Purity: 98.59%
Catalog No. T18353
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used to synthesise PROTAC molecules. Methyltetrazine-PEG5-methyltetrazine contains a Tetrazine moiety, which can be used in an iEDDA click chemistry reaction with molecules containing TCO moiety.
Pack SizePriceAvailabilityQuantity
1 mg$71In Stock
5 mg$166In Stock
10 mg$265In Stock
25 mg$478In Stock
50 mg$713In Stock
100 mg$986In Stock
200 mg$1,320In Stock
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Purity:98.59%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Methyltetrazine-PEG5-methyltetrazine is a PEG-based PROTAC linker that can be used to synthesise PROTAC molecules. Methyltetrazine-PEG5-methyltetrazine contains a Tetrazine moiety, which can be used in an iEDDA click chemistry reaction with molecules containing TCO moiety.
Chemical Properties
Molecular Weight704.78
FormulaC34H44N10O7
SmilesCC1=NN=C(C2=CC=C(CNC(CCOCCOCCOCCOCCOCCC(NCC3=CC=C(C4=NN=C(C)N=N4)C=C3)=O)=O)C=C2)N=N1
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PEGsMethyltetrazine-PEG5-methyltetrazineMethyltetrazine-PEG-5-methyltetrazineMethyltetrazinePEG5methyltetrazineMethyltetrazine PEG5 methyltetrazine
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