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LAP

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Catalog No. T32568Cas No. 85073-19-4
Alias Lithium PTMB phosphinate, Lithium phenyl-2,4,6-trimethylbenzoylphosphinate

LAP is a highly efficient and biocompatible radical photoinitiator used to initiate radical chain polymerisation and synthesise polymeric materials under light irradiation. The primary wavelength for light absorption and polymerisation initiation is 405 nm. LAP concentrations ≥3.4 mmol/L and the radicals it generates exhibit cytotoxicity towards M-1 mouse renal collecting duct cells.

LAP

LAP

😃Good
Purity: 99.89%
Catalog No. T32568Alias Lithium PTMB phosphinate, Lithium phenyl-2,4,6-trimethylbenzoylphosphinateCas No. 85073-19-4
LAP is a highly efficient and biocompatible radical photoinitiator used to initiate radical chain polymerisation and synthesise polymeric materials under light irradiation. The primary wavelength for light absorption and polymerisation initiation is 405 nm. LAP concentrations ≥3.4 mmol/L and the radicals it generates exhibit cytotoxicity towards M-1 mouse renal collecting duct cells.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$40In StockIn Stock
500 mg$77-In Stock
1 g$123-In Stock
1 mL x 10 mM (in DMSO)$45In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.89%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
LAP is a highly efficient and biocompatible radical photoinitiator used to initiate radical chain polymerisation and synthesise polymeric materials under light irradiation. The primary wavelength for light absorption and polymerisation initiation is 405 nm. LAP concentrations ≥3.4 mmol/L and the radicals it generates exhibit cytotoxicity towards M-1 mouse renal collecting duct cells.
SynonymsLithium PTMB phosphinate, Lithium phenyl-2,4,6-trimethylbenzoylphosphinate
Chemical Properties
Molecular Weight295.22
FormulaC16H17LiO3P
Cas No.85073-19-4
Smiles[Li].O=C(C=1C(=CC(=CC1C)C)C)P(=O)(O)C=2C=CC=CC2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 6 mg/mL (20.32 mM), Sonication is recommended.
DMSO: 20 mg/mL (67.75 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.77 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM3.3873 mL16.9365 mL33.8730 mL169.3652 mL
5 mM0.6775 mL3.3873 mL6.7746 mL33.8730 mL
10 mM0.3387 mL1.6937 mL3.3873 mL16.9365 mL
20 mM0.1694 mL0.8468 mL1.6937 mL8.4683 mL
DMSO
1mg5mg10mg50mg
50 mM0.0677 mL0.3387 mL0.6775 mL3.3873 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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