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Denagliptin

Name: Denagliptin
Brand: TargetMol
SKU: T68053
Price: 191 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T68053Cas No. 483369-58-0

Alias GW823093

Denagliptin is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of endocrine Ü metabolic diseases and can be used in the study of type 2 diabetes.

Denagliptin

🥰Excellent

Purity: 99.12%

Catalog No. T68053Alias GW823093Cas No. 483369-58-0

Denagliptin is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of endocrine Ü metabolic diseases and can be used in the study of type 2 diabetes.

Pack Size	Price	Availability
1 mg	$191	In Stock
5 mg	$480	In Stock
10 mg	$687	In Stock
25 mg	$1,080	In Stock
50 mg	$1,480	In Stock
100 mg	$1,990	In Stock
500 mg	$3,920	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.12%

ee:99.01%

Resource Download

COA LCMS CSFC FNMR HNMR ORP

Product Introduction

Bioactivity

Description	Denagliptin is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor for the treatment of endocrine Ü metabolic diseases and can be used in the study of type 2 diabetes.
Synonyms	GW823093

Chemical Properties

Molecular Weight	373.37
Formula	C₂₀H₁₈F₃N₃O
Cas No.	483369-58-0
Smiles	C([C@@H](C(=O)N1[C@H](C#N)C[C@H](F)C1)N)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (133.92 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6783 mL	13.3915 mL	26.7831 mL	133.9154 mL
5 mM	0.5357 mL	2.6783 mL	5.3566 mL	26.7831 mL
10 mM	0.2678 mL	1.3392 mL	2.6783 mL	13.3915 mL
20 mM	0.1339 mL	0.6696 mL	1.3392 mL	6.6958 mL
50 mM	0.0536 mL	0.2678 mL	0.5357 mL	2.6783 mL
100 mM	0.0268 mL	0.1339 mL	0.2678 mL	1.3392 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc