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15(S)-15-methyl Prostaglandin F2α isopropyl ester

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Catalog No. T36155Cas No. 157283-72-2
Alias 15(S)-15-methyl Prostaglandin F2α isopropyl ester

15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid.

15(S)-15-methyl Prostaglandin F2α isopropyl ester

15(S)-15-methyl Prostaglandin F2α isopropyl ester

😃Good
Catalog No. T36155Alias 15(S)-15-methyl Prostaglandin F2α isopropyl esterCas No. 157283-72-2
15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid.
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1 mg$57Backorder
5 mg$271Backorder
10 mg$484Backorder
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Product Introduction

Bioactivity
Description
15(S)-15-methyl Prostaglandin F2α (15(S)-15-methyl PGF2α) has been shown to have potent uterine stimulant and abortifacient properties when administered intramuscularly to induce labor. 15(S)-15-methyl PGF2α isopropyl ester is a lipophilic analog of 15(S)-15-methyl PGF2α methyl ester, which may be hydrolyzed in vivo to the fully active free acid.
Synonyms15(S)-15-methyl Prostaglandin F2α isopropyl ester
Chemical Properties
Molecular Weight410.595
FormulaC24H42O5
Cas No.157283-72-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 20 mg/mL (48.71 mM), Sonication is recommended.
DMSO: 20 mg/mL (48.71 mM), Sonication is recommended.
Ethanol: 50 mg/mL (121.77 mM), Sonication is recommended.
PBS (pH 7.2): 2 mg/mL (4.87 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMF/DMSO/Ethanol
1mg5mg10mg50mg
1 mM2.4355 mL12.1774 mL24.3549 mL121.7745 mL
DMF/DMSO/Ethanol
1mg5mg10mg50mg
5 mM0.4871 mL2.4355 mL4.8710 mL24.3549 mL
10 mM0.2435 mL1.2177 mL2.4355 mL12.1774 mL
20 mM0.1218 mL0.6089 mL1.2177 mL6.0887 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

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