Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Transferrin Receptor/TFRC Protein, Cynomolgus, Recombinant (His)

(Synonyms: TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71) Copy Product Info

Synonyms: TR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71

Catalog No. TMPK-01261 Copy Product Info
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 76.3 kDa and the accession number is XP_005545315.1.

Product Introduction

Bioactivity
Bioactivity
Immobilized Cynomolgus Transferrin R, His Tag at 2 μg/mL (100 μL/well) on the plate. Dose response curve for Biotinylated Human Transferrin, His Avi Tag with the EC50 of 12.9 ng/mL determined by ELISA.(QC Test)
Description
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status. Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 76.3 kDa and the accession number is XP_005545315.1.
Species
Cynomolgus
Expression System
HEK293 Cells
TagN-His
Accession NumberXP_005545315.1
ConstructionCys89-Phe760
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsTR, TFRC, TfR1, TFR, T9, sTfR, p90, CD71
Research Background
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
Chemical Properties
Molecular Weight76.3 kDa (predicted). Due to glycosylation, the protein migrates to 78-80 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Calculator

  • Reconstitution Calculator
  • Recombinant Protein Dilution Calculator
  • Specific Activity Calculator

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Keywords

Related Tags: Transferrin Receptor/TFRC Protein, Cynomolgus, Recombinant (His) chemical structure | Transferrin Receptor/TFRC Protein, Cynomolgus, Recombinant (His) molecular weight