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Azido-PEG4-azide

Catalog No. T39268 CAS 182760-73-2

Azido-PEG4-azide is a PEG-based PROTAC Linker that can be used to synthesize PROTACs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Azido-PEG4-azide, CAS 182760-73-2

Pack Size	Availability	Price/USD
5 mg	In stock	$ 50.00
10 mg	In stock	$ 70.00
25 mg	In stock	$ 114.00
50 mg	In stock	$ 167.00
100 mg	In stock	$ 248.00
500 mg	In stock	$ 535.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Azido-PEG4-azide is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
In vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].

Molecular Weight	288.3036
Formula	C10H20N6O4
CAS No.	182760-73-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Related Products

Related compounds with same targets

Pomalidomide-PEG3-C2-NH2 NH2-C6-NH-Boc (+)-Biotin-ONP NH2-C4-NH-Boc Acid-C1-PEG5-Boc BM-PEG3 Boc-NH-PEG4-CH2COOH Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Azido-PEG4-azide 182760-73-2 PROTAC PROTAC Linker inhibit Inhibitor PROTAC Linkers Azido PEG4 azide AzidoPEG4azide Azido-PEG-4-azide inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.