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1-Benzyl-3-Phenylthiourea

Name: 1-Benzyl-3-Phenylthiourea
Brand: TargetMol
SKU: T77663
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77663Cas No. 726-25-0

Alias 1-Benzyl-3-Phenyl-2-Thiourea

1-Benzyl-3-Phenylthiourea (1-Benzyl-3-Phenyl-2-Thiourea) can be used as a sensing material for the detection of nerve agents and related stimulants.

1-Benzyl-3-Phenylthiourea

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Purity: 99.98%

Catalog No. T77663Alias 1-Benzyl-3-Phenyl-2-ThioureaCas No. 726-25-0

1-Benzyl-3-Phenylthiourea (1-Benzyl-3-Phenyl-2-Thiourea) can be used as a sensing material for the detection of nerve agents and related stimulants.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

1-Benzyl-3-Phenylthiourea AI Summary

1-Benzyl-3-Phenylthiourea exhibits significant bioactivities related to melanogenesis inhibition. It shows inhibitory effects on mushroom tyrosinase activity, with a percentage inhibition of less than 10% and an IC50 value greater than 100,000 nM. Moreover, it demonstrates a notable inhibition (91%) of alpha-MSH-stimulated melanogenesis in mouse B16 cells, with an IC50 value of 4700.0 nM. Additionally, 1-Benzyl-3-Phenylthiourea inhibits the activity of Pseudomonas aeruginosa PvdP tyrosinase, with an IC50 value of 19,400.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	1-Benzyl-3-Phenylthiourea (1-Benzyl-3-Phenyl-2-Thiourea) can be used as a sensing material for the detection of nerve agents and related stimulants.
Synonyms	1-Benzyl-3-Phenyl-2-Thiourea

Chemical Properties

Molecular Weight	242.34
Formula	C₁₄H₁₄N₂S
Cas No.	726-25-0
Smiles	S=C(NCC1=CC=CC=C1)NC1=CC=CC=C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (206.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1264 mL	20.6322 mL	41.2643 mL	206.3217 mL
5 mM	0.8253 mL	4.1264 mL	8.2529 mL	41.2643 mL
10 mM	0.4126 mL	2.0632 mL	4.1264 mL	20.6322 mL
20 mM	0.2063 mL	1.0316 mL	2.0632 mL	10.3161 mL
50 mM	0.0825 mL	0.4126 mL	0.8253 mL	4.1264 mL
100 mM	0.0413 mL	0.2063 mL	0.4126 mL	2.0632 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc