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Anti-Profilin 2 Antibody (4O556) is a Rabbit antibody targeting Profilin 2. Anti-Profilin 2 Antibody (4O556) can be used in WB,ELISA.
Description | Anti-Profilin 2 Antibody (4O556) is a Rabbit antibody targeting Profilin 2. Anti-Profilin 2 Antibody (4O556) can be used in WB,ELISA. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 4O556 |
Reactivity | Human |
Verified Activity | Anti-PFN2 rabbit monoclonal antibody at 1:500 dilution. -Lane A: NCI-H1299 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:15 kDa. -Observed band size:15 kDa |
Application | WB,ELISA |
Recommended Dose | WB: 1:500-1:1000; ELISA: 1:25000-1:50000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Profilin 2 / PFN2 (rh Profilin 2 / PFN2; TMPY-03657; AAH18049.1; Met1-Phe140). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Profilin 2, also known as PFN2, is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver. Profilin 2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. Profilin 2 is thought to regulate actin polymerization in response to extracellular signals. It inhibits the formation of IP3 and DG by binding to PIP2. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Profilin 2 / PFN2 Protein (TMPY-03657) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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